Two researchers at the Department of Inorganic Chemistry at the University of Alcalá , Francisco Javier de la Mata and Rafael Gomez (Image 1) have made an important discovery in the field of medicine. They have discovered that carbon and silicon, two elements that are present in our environment, could be the basis of a new AIDS treatment, less toxic and effective at doses lower than those currently available. Furthermore, this treatment could curb the disease within infected cells.
The key to this new treatment would be in carbosilane dendrimers (in Figure 2 a dendrímetro simulated structure), which are "three-dimensional molecules containing carbon -silicon, are capable of binding to cell nucleic material, protect and transport it to the inside of the cells infected by HIV ". So "by facilitating the inhibition of virus, slow expansion to other cells" , these researchers explain.
Francisco Javier and Rafael are immersed for more than five years in this research project, in collaboration with the Laboratory of Molecular Immunology of the Hospital Gregorio Maranon de Madrid . Now the results have been embodied in a patent has been awarded in the Contest Madrid 2008 the best patents. In this event the jury highlighted "the importance of the invention of the patent and the expected impact of it in the field of biomedicine, as well as internationalization strategy developed" .
But also the role of the dendrimers does not end here, as researchers at the University of Alcalá are collaborating with the University of Navarra to achieve effective cancer dendrimers. They also have launched a collaborative project with the Universidad Complutense, and work together with research groups from France, Germany, Czech Republic or Poland in the international arena. With the latter are conducting a study on the ability of these molecules in biomedicine, with the aim of using them as agents in antipriónicos treatment of Alzheimer's.
SOURCE: Europapress
SOURCE: Europapress
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